Parental and neonatal risk factors for atopy, airway hyper-responsiveness, and asthma.
نویسندگان
چکیده
منابع مشابه
Parental and neonatal risk factors for atopy, airway hyper-responsiveness, and asthma.
BACKGROUND Previous studies have not resolved the importance of several potential risk factors for the development of childhood atopy, airway hyperresponsiveness, and wheezing, which would allow the rational selection of interventions to reduce morbidity from asthma. Risk factors for these disorders were examined in a birth cohort of 1037 New Zealand children. METHODS Responses to questions o...
متن کاملAtopy, airway responsiveness, and genes.
Asthma is a manifestation of bronchial hyperreactivity (BHR) and forms part of the spectrum of atopic disease. Some pedigree studies of atopy have suggested linkage with the high-affinity IgE receptor (FcE RI1) gene on chromosome 11q13, but others find no linkage. The molecular genetics of asthma and BHR have not been studied in the general population. We examined the genetic linkage of the Fce...
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Asthma is a condition characterized by recurrent breathlessness, cough or wheeze caused by variable or intermittent narrowing of intrapulmonary airways [ 13. All asthmatic individuals have hyper-responsive intrathoracic airways and because of this most experience acute attacks of bronchoconstriction at times. A great deal of work has been done to understand this hyperresponsive state of the air...
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Background and purpose: Asthma is a chronic inflammatory disease of the airways that is caused by hypersensitivity to environmental allergens. Symptoms of asthma include shortness of breath, airway hyper-responsiveness, wheezing, and cough. The disease might vary from a mild to severe and intermittent to chronic disease. Asthma is known as a multifactorial disease due to the interaction of gene...
متن کاملEnvironmental tobacco smoke, parental atopy, and childhood asthma.
We hypothesized that the joint effect of genetic propensity to asthma and exposure to environmental tobacco smoke on the risk of childhood asthma is greater than expected on the basis of their independent effects. We performed a population-based 4-year cohort study of 2,531 children born in Oslo, Norway. We collected information on the child's health and environmental exposures at birth and whe...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1996
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.75.5.392